I think that logic works down the line as well. You want Henderson to go game 2 so that he's available out of the bullpen in game 5 if necessary.
I get OP's logic. Your opponent is going to throw their #1 in games 2 and 5, so why not put Miz against them. That's where having the strong #2 comes in handy to put against the opponent's #1.
Assuming it's the Padres, I'd do a Patrick opener to Gasser in game 3 to attack their platoon vulnerabilities against LHP.
Then start May on a short leash in G4, followed by a lefty reliever to attack their platoons again.