I'm somewhat familiar with the Advertising field. Forget obsessing about the resume. Yes, you need to send them- it's worth a try. However, 99% chance you can keep sending them and nothing will happen. Didn't you intern somewhere in college? Are you on LinkedIn, and joined the Milw, Madison, and Chicago groups? Doesn't each city have an association, or professional group of some kind that had regular outings? Bottom line, entry jobs are filled with people who interned for these firms in college. Plus, and sorry but this is just true, preference is for attractive females. Not looking to stir up controversy, it's just true. Why not start your own business? Offer your services for free or nominal amount and build a client base and portfolio. Before long, you can start charging more. You can also now approach agencies with a client list you can bring to them. Another idea, you are in a creative field so....be creative. Sending resumes to HR depts. is not creative. Think outside the box. Look at the client list of the place you're applying and put together a press release, or print ad, radio ad...whatever for one of their clients. Show them what you can do! Find the creative people in the agency, not PR. Lots of different ways to get noticed, don't be afraid to get a little crazy, yet stay professional. Nothing to lose right?