I used to have the next-larger version (US-244?) of this, and it was great. It pretty much acts as a sound card, and whichever software you use can allow it to act as a multitrack recorder. I used Cubase SX several years ago (as well as its predecessor, I believe was simply called Cubase), and it was very nice, though a bit buggy at times. I haven't done any music stuff in awhile, but I'm sure it's much more stable now. Nuendo is pretty much the same software IIRC, they're made by the same company have have almsot identical interfaces. I mostly used it for sequencing, but it definitely well for recording.