Only in very specific situations. Situations that don't come up very often. The difference is even smaller when you take out the at bats with hits or walks. Edit: Fielder has 42 PA with a guy on 3B and less than 2 outs.(I am assuming he leads the team in PA with a guy on 3B and less than 2 outs, if he doesn't he will be close) Unless you are talking about one guy who strikes out every single time vs a guy who flies out every single time, it will make very little difference over a whole year. A handful of runs over a whole year.