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LouisEly

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Everything posted by LouisEly

  1. I think it would be completely insane NOT to send them back. The long term psychological and physical effects from children not socializing for many months up to several years are not known. https://www.wpr.org/high-school-athletes-experiencing-increased-anxiety-depression-during-pandemic-study-shows
  2. Oh yes, if you factor in the costs of the drugs that fail it's going to be closer to $2B, but I was referring to bringing that specific drug to market. As for the "bounty" idea, that is somewhat already in place now. Several states have basically "bid out" treating their Hepatitis-C patient population to pharma companies - the states will pay a flat fee to the pharma company to treat their entire population of Hepatitis-C patients instead of the states being billed through medicaid on a per-patient basis. Because the new treatments have a 98% cure rate, there really aren't any recurring costs of chronic care.
  3. No, you're not following this correctly. Remdesivir was developed more than a decade ago as a Hepatitis-C treatment (didn't work well), and then studied as an Ebola treatment. It takes years to develop a drug, so they are testing available drugs already on the market that have anti-viral or anti-inflammatory effects with the potential to counteract some of the known or hypothesized pathways of the disease. As a FYI, the "cost" (before rebates, discounts, etc.) of an average Hepatitis-C drug is over $50K for about 8-12 weeks of treatment. Peter Maybarduk, a lawyer at the consumer group Public Citizen, called the price “an outrage.” “This is a drug that received at least $70 million in public funding” toward its development, he said. “Remdesivir should be in the public domain.” “The price puts to rest any notion that drug companies will ‘do the right thing’ because it is a pandemic,” Dr. Peter Bach, a health policy expert at Memorial Sloan Kettering Cancer Center in New York said in an email. “The price might have been fine if the company had demonstrated that the treatment saved lives. It didn’t.” I have no idea where you are quoting that from, but it costs $500M to $1B to develop a drug and bring it to market. $72M is a drop in the bucket when it comes to drug development costs, probably about 10% of the total development cost, and they have discounted remdesivir well over 10% for $3200/treatment. Now, if you're referring to funding a study, that's a different story, as you haven't provided a link to whatever you are quoting that from. But drug development is damn expensive, and remdesivir wasn't developed to treat COVID-19.
  4. No, you're not following this correctly. Remdesivir was developed more than a decade ago as a Hepatitis-C treatment (didn't work well), and then studied as an Ebola treatment. It takes years to develop a drug, so they are testing available drugs already on the market that have anti-viral or anti-inflammatory effects with the potential to counteract some of the known or hypothesized pathways of the disease. As a FYI, the "cost" (before rebates, discounts, etc.) of an average Hepatitis-C drug is over $50K for about 8-12 weeks of treatment.
  5. See the link in my post above (and below):
  6. Well, the contact tracing has shown much of the spread to be coming from bars and graduation parties. Supposedly 50% is from people under 30.
  7. Can you share data/research that supports this? From what I've seen, the PM2.5 filter that is inside of them covers the entire face covering, and it does not seem possible for air to not go through the filter whether they are inhaling or exhaling. Also, the vent is on the side of the face, not in front of the mouth/nose where someone is breathing/speaking - it's on the side of their mouth where very few droplets are going out. A vast majority of droplets are going into the cloth in front of the mouth/nose. I find it really, really hard to believe that they are not at least 90% as effective as a non-filtered masks.
  8. All of the data for all of the states and countries reporting, plus projections: https://covid19.healthdata.org/united-states-of-america Interesting that even with the recent spikes, they are not projecting the daily total number of deaths to rise for the next couple of weeks.
  9. Bulaga may have started 16 games, but he only played 83.6% of offensive snaps so he missed the equivalent of 2.63 games. Plus, in 2018 he only played 72.7% of snaps and two seasons ago (2017) he missed 11 games and he's on the wrong side of 30. And, like others have said, I think would have been difficult for them to sign Bulaga, Clark, and Bakh. I think your last sentence is correct, but for Nijman, not Light. They added Nijman to the active roster at the end of November, so they think highly of him. I think they want him to get one more year as a backup before trusting him to protect Rodgers, thus the signing of Wagner as a stopgap (while technically a 2-year deal, NFL FA contracts are usually for a year longer than they are intended to be for and I doubt he sees year two).
  10. One of the Royal Rumbles, I believe 2008, is on FS1 right now. One of the matches is MVP vs. Rick Flair. I don't remember MVP being that big of a deal.
  11. I have a relative who is an administrative position with a large hospital system in the Eau Claire area. He said their ICU is full, but only four of them are COVID patients. I asked if they have had an abnormal amount of accidents, heart attacks, etc., and he said that most of them were people who waited to get treatment (assuming out of fear of coming into a medical facility) and waited too long.
  12. If you donate blood they will do antibody testing for you for free. At least, Vitalant will (I go to the one on Fullerton).
  13. That's pretty much Chicago, except in Chicago you can't go on the beach and the "boardwalk" (a.k.a. lakefront trail) is closed (until Monday).
  14. This is pretty much what I recall. The initial focus was on contracting COVID, of which only N95 masks prevent inhaling it; cloth masks don't do much to protect against inhaling it. I'm totally OK with them "lying" to the public about masks to prevent hoarding of the N95 masks. Hell, look at the hoarding of toilet paper that happened - can you imagine the hoarding of N95 masks that would have happened? If that hoarding of N95 masks had happened, how many more health care workers would have contracted COVID-19? How many fewer healthcare workers would have been available to treat patients because they contracted the virus or because they didn't have access to N95 masks? How many more lives would that have cost? As we saw with many things over the last three months, people are selfish and opportunistic, and sometimes not telling the whole truth is the only way to prevent that.
  15. The American Academy of Allergies, Asthma, and Immunology has stated that there is no increased infection risk among those who have asthma: https://www.aaaai.org/conditions-and-treatments/library/asthma-library/covid-asthma This has been corroborated by research from the University of Wisconsin, which showed that allergic asthma in adults may actually have a protective benefit and lower increased infection risk.
  16. I think you're spot-on.
  17. No kidding. Between the people who can't be bothered to just wear a damn mask (and gloves) indoors in public places, and the people who are at the other end of the spectrum who are high risk and think that just because they shouldn't do something that nobody else should be able to either and they should shut down everything for everyone. As for the protests, I don't think they will cause much of a spike because they were outdoors and during the daytime when it was usually sunny. We're two weeks past the protests, three weeks past the riots, so if there is a spike we should be seeing it now. Here's Illinois new cases by day over the last 30 days - slight trend up the last six days, but not spiking at all:
  18. "Hey, I don't need no marijuana, man... and I don't need no acid, man... 'Cause I'm hooked on downers." (Thud)
  19. Assuming you mean "white collar", which is false. I've spent most of my career in pharma and it's been a part of every drug screen I've ever taken for employment. One company I worked for did random drug screens of the sales force (assuming because they have company cars). Drug screens have included hair follicle tests, not just urine samples. Very few start-ups, if any, test, and typically (except for the one company that did random drug tests) they don't test again after you are hired, but to say they don't test for white collar jobs is patently false.
  20. Costs money to clean the dining room/restrooms, take out that garbage, stock the napkins/straws/soda machine/paper towel/toilet paper, etc., and if they're getting just as much business via the drive thru - or close enough that the added revenue isn't worth the extra costs - then there is no incentive to reopen the dining area.
  21. I think what Boomer is saying here is that IF governors try to put another lockdown in place and ban gatherings, shut down parks, no more outdoor dining at restaurants, etc., the public will call BS and say that they allowed these protests which are no different, if not worse, than having a small gathering, dining outdoors, going to the park, etc.
  22. Zavier Warren had a .502 OBP last year.
  23. 3rd round: Daniel Susac Alejandro Rosario Nick Frasso
  24. Don't know anything about these guys, but there is a grouping of four college arms around the range of our 2nd pick (#53) on the composite rankings Eye Black posted a few pages back... 49 | Nick Swiney | LHP | North Carolina State 50 | Cole Henry | RHP | Louisiana State 51 | Tommy Mace | RHP | Florida 52 | Logan Allen | LHP | Florida International Also caught a blurb on FG about Landon Knack (#113 on EB's composite rankings) out of East Tennessee State who apparently had a velocity bump this year & posted 51 Ks versus only 1 BB in 25 IP before the shutdown. Maybe a guy in play for our 3rd pick at 92? I was just going to point out Swiney and Allen as the two guys I have a feeling the Brewers could be targeting. High K rates, Swiney historically had a somewhat high walk rate but in limited action this year has reduced it, Allen historically lower on the walk rate.
  25. Regeneron has started human trials of a combination of two antibodies (whereas Eli Lilly's drug is a single antibody): https://www.cnn.com/2020/06/11/health/regeneron-covid-19-antibody-trial-starts/index.html Before people get too excited, it sounds like both/any antibody treatments will initially be reserved for the high-risk populations (elderly, immunocompromised) and healthcare/essential workers, unless you actually get infected bad enough to get hospitalized. Regeneron has been preparing for a pandemic for years, developed a successful Ebola treatment last year, and developed the antibody treatment in two months.
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