Santana - pitches 1-15 - .733 , inn 1 - .681, overall - .592 Oswalt - pitches 1-15 - .785 , inn 1 - .687, overall - .694 Carpenter - pitches 1-15 - .690, inn 1 - .624, overall - .645 Halladay - pitches 1-15 - .589, inn 1 - .639, overall - .650 (freak!) Peavy - pitches 1-15 - .678, inn 1 - .687, overall - .670 Zambrano - pitches 1-15 - .692, inn 1 - .597, overall - .646 Mussina - pitches 1-15 - .724, inn 1 - .732, overall - .723 Once you get into the mediocre pitchers I tended to notice that they had a lot more troubles in the late innings but they still trended to have higher 1st inning reducing until the 4th where it spikes up again. Sheets is kind of a strange case with the 3 year splits. In the past 3 years he's had 278 AB's against him in the 1st inning which I didn't really feel was enough AB's which is why I looked at his career trends. In his career he's been .740 OPS against 1st inning, .718 OPS against total which is right in line with the majority of those pitchers I listed.