It depends... I think you have to know the health situation of Stokes and the depth of the draft at those positions.
Safety is easily our biggest need. But if there are similarly ranked players in the second round (which looks like it this year), I'd defer. So I think it comes down to OT and CB. Both are in a similar situation with Valentine/Alexander vs Tom/Walker. If Stokes' recovery (actually) looks positive, I'd lean OT. If not... you normally play 3-4 CBs but only 2 OTs at one time...
Frankly, your first round should be reserved to drafting CBs, OTs, Edge, QBs, or WRs. Those are the skill positions that seem to have a major edge over players in following rounds.
Gs, Cs, TEs, RBs, DTs, MLBs, and Ss seem to be much easier to find in the second and following rounds that are nearly as good as their first round counterparts. Please don't waste your time listing the exceptions. We know they are there, but they are exceptions for a reason. The rarity of them proves my point.