I live 10 minutes outside of the city, happy to help! For those without kids, the nightlife isn't too far from the stadium. Laclede's Landing is always popular, expect covers at most places. Washington Ave can trend a slight bit older (maybe a little more 30s than 20s). Depending on if you have a DD, I prefer Westport, which is on the North western side of the city. As far as during the day, the Arch may be obligatory, but I found it a waste of time. The Bud tour isn't bad, and last time I went, they had Clydesdales there. I haven't seen the MvF episodes, but guessing Crown Candy, and maybe Pappys is on there. If you're BBQ fans, check out both Pappys (near SLU), and Bogarts (in Soulard, not far from downtown). Vastly different, but equally excellent. May want to check out Ted Drewes frozen custard, it's pretty good. Casinos are always fun, the Lumiere has good restaurants as well. For those with kids, most of the same applies. City museum is pretty cool, regardless of age. Forrest Park is really nice, the zoo, a number of museums, and a whole lot of other things to do in there. STL has a really nice zoo, if they're at all interested, it's worth it. If anyone has specific restaurant questions (best place for..) feel free to ask. I will give my non-expert opinion! I'm sure it's been mentioned, but STL isn't really a tailgating city for Cardinals games. The stadium is in the middle of downtown, so most parking is garage parking.