I agree with sbryl, I think it's position dependent. If you draft a 3B or C who is deficient, he's likely going to end up in a corner spot, or maybe 1B. That certainly makes him less valuable. However, if a player projects as a good enough ML hitter, I don't think position/defensive ability matter much at all. For instance, I can't imagine Billy Butler won't hit enough to find a position on the diamond, although he will likely DH a lot in the AL. I actually think it's more difficult to take a plus defender/weak bat in the NL, where you already have the pitcher stinking in the 9 hole.