No, but you should remove him when he's at a high number of pitches and he's leading off an inning in a game when you're behind. Just because some pitchers can do it, doesn't mean all of them can. Why take the risk of over pitching the staff ace (for the future, and the future of this season), when you don't know if he can handle it, or if the extra workload will break him down? Injury histories, and histories of pitcher abuse *HAVE* shown that the extra 300-500 pitches DO matter. From http://www.baseball-analysis.com/article.php?articleid=2633 This isn't something that's just made up. Especially for young pitchers, high pitch counts lead to MUCH higher injury risks.