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Pirates (Keller) vs Brewers (Misiorowski): 4/25/26, 6:10pm

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Right-hander Mitch Keller makes his 13th career start against Milwaukee. Keller faced the Brewers three times in 2025, pitching well at PNC Park (twice) and poorly at American Family Field (once). The Brewers beat Keller twice last season. Keller has a lifetime 5.31 ERA and 1-7 record against the Brewers.

Jacob Misiorowski makes his third career start against Pittsburgh. Miz is 2-0 with 0.75 ERA over 12 career IP against the Pirates.

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